Guhan Jayaraman

Phone: 91-44-2257-4108

2009 – Present: Professor
2001 – 2009 : Associate Professor

Sivapuratharasan, V., Lenzen, C., Michel, C., Muthukrishnan, A.B., Jayaraman, G., Blank, L.M. Metabolic engineering of Pseudomonas taiwanensis VLB120 for rhamnolipid biosynthesis from biomass-derived aromatics (2022) Metabolic Engineering Communications, 15, art. no. e00202, DOI: 10.1016/j.mec.2022.e00202
Ashokan, A., Kumar, T.S.S., Jayaraman, G.Process optimization for the rapid conversion of calcite into hydroxyapatite microspheres for chromatographic applications(2022) Scientific Reports, 12 (1), art. no. 12164, . DOI: 10.1038/s41598-022-16579-4
Rathinavelu, S., Divyapriya, G., Joseph, A., Nambi, I.M., Muthukrishnan, A.B., Jayaraman, G. Inactivation behavior and intracellular changes in Escherichia coli during electro-oxidation process using Ti/Sb-SnO2/PbO2 anode: Elucidation of the disinfection mechanism (2022) Environmental Research, 210, art. no. 112749, . Cited 2 times.DOI: 10.1016/j.envres.2022.112749
Jeeva, P., Jayaprakash, S.R., Jayaraman, G.Hyaluronic acid production is enhanced by harnessing the heme-induced respiration in recombinant Lactococcus lactis cultures (2022) Biochemical Engineering Journal, 182, art. no. 108428, . DOI: 10.1016/j.bej.2022.108428
Rajendran, V., Pushpavanam, S., Jayaraman, G.Continuous refolding of L-asparaginase inclusion bodies using periodic counter-current chromatography (2022) Journal of Chromatography A, 1662, art. no. 462746, . DOI: 10.1016/j.chroma.2021.462746

Engineering Bacterial Chassis and Development of Bioprocess Strategies for Efficient Bioconversion of Lignocellulosic Sugars to Platform Chemicals” (2024 – 2027), DBT-funded; Amount sanctioned – Rs. 85.38 lakhs
Chemical and biological upgradation of waste sugarcane bagasse lignin into dicarboxylic acids via a novel approach (2024 – 2027), DBT-funded; Amount sanctioned – Rs. 88.92 lakhs
Chemo-microbial upgradation of waste plastics to platform chemicals (2024-2025) ; Intra-mural funding from School of Sustainability (PI – Dr. Krithika Ravi; co-PIs – Dr. Guhan Jayaraman and Dr. Dr. Vinu); funds sanctioned – Rs. 20 lakhs
Model Predictive Control of Hyaluronic Acid Production using in-situ Near-Infrared (NIR) spectroscopy (2024-2027); SERB-funded project (PI- Dr. Nirav Bhatt; co-PI – Dr. Guhan Jayaraman); funds sanctioned – Rs. 29 lakhs
Infrastructure and Development of Technologies for Pre-clinical evaluation, Product establishment and Platform integration for Onco-theranostic applications (2022 – 2025); SERB-funded joint project with Cancer Institute (WIA); Total funds sanctioned ~ Rs. 470 lakhs; Amount sanctioned to IITM ~ Rs. 270 lakhs

Shivansh Goyal, Sudeshna Sengupta and Guhan Jayaraman (PCT Filed Nov 2018), Method for direct quantification of nucleic acids in real-time qPCR, US Patent No. 11,603,561 B2 (Granted March 2023)
Kirubhakaran Puvendran and Guhan Jayaraman (Filed 2019), Process for production of high molecular weight hyaluronan in recombinant Lactococcus lactis using acetate co-utilization fed-batch strategy, Indian Patent No. 412658 (Granted 2022)
Sreeja Shanmuga Doss, Pandeeswari Jeeva and Guhan Jayaraman (Filed 2018), Process Strategies for production of hyaluronic acid at constant molecular weight during recombinant bacterial fermentations, Indian Patent No. 408543 (Granted 2022)
Shivansh Goyal, Sudeshna Sengupta and Guhan Jayaraman (Filed 2017), Method for direct quantification of nucleic acids in real-time qPCR, Indian Patent No. 393411 (Granted 2022)
Cramer,S.M., J.A. Moore, Y. Li, A. Kundu and G. Jayaraman (1995), Displacement Chromatography of Proteins using Low Molecular Weight Displacers, S. Patent No. 5,478,924
Cramer,S.M., G. Jayaraman, A. Kundu, Y. Li and J.A. Moore (1997), Protein Purification at Process Scale by Displacement Chromatography using Low Molecular Weight Anionic Displacers, S. Patent No. 5,606,033

Trendsetter Award, IITM Energy Consortium (2024)
Winner, Grand Innovation Challenge, 1^st Global Innovation Summit (2021) organized by the Indian Pharmaceutical Alliance
BIRAC Innovator Award 2019 (shared with AlgalR Nutrapharms, Thanjavur)
International Genetically-Engineered Machines Competition (iGEM) 2008 : Foundational Advances Award and Best Engineered Biobrick Award (as Mentor of IITM iGEM team which won the awards)